Proteolea®

Proteolea® is one of O COSMEDICS Core Four functional actives, chosen for its ability to target glycation: one of the five major causes of aging. Glycation is a biochemical process where excess glucose attaches to collagen fibres causing them to stiffen, weaken and lose elasticity. Proteolea® helps slow this process by reducing the formation of advanced glycation end products (AGEs) while supporting the renewal of healthier collagen structures.

This advanced complex also helps reactivate the skin’s proteasome pathway, a natural cellular recycling system responsible for removing damaged or dysfunctional proteins. By supporting this renewal cycle Proteolea® helps maintain clearer pathways for new, stronger collagen to form contributing to visibly smoother, firmer and more vibrant looking skin.

As a modern day essential, Proteolea® also provides critical defence against HEV blue light exposure from digital screens which can trigger oxidative stress. With strong antioxidant and anti-inflammatory benefits it helps maintain skin clarity, brightness and calm.

Benefits For The Skin

  • Helps reduce the formation of AGEs, advanced glycation end products
  • Supports the recycling and renewal of damaged collagen fibers
  • Helps defend skin from high energy visible light (HEV/blue light) induced oxidative stress
  • High antioxidant activity to support long term skin longevity
  • Helps reduce visible inflammation for a calmer skin
  • Supports collagen quality for firmer more youthful looking skin

Form, Stability & Delivery

Proteolea® is a stable, multifunctional active easily incorporated into serums, cleansers and creams. Its compatibility with O’s biomimetic technology ensures efficient delivery without compromising barrier integrity. When paired with liquid crystal and encapsulated systems it reaches targeted pathways with high precision and minimal irritation.

How Proteolea® Works - Made Simple

1. Anti-Glycation Support
Proteolea® helps reduce the binding of sugars to collagen fibres, limiting the formation of rigid, brittle structures associated with accelerated aging and loss of skin suppleness.

2. Protein Recycling and Renewal
By supporting the skin’s natural proteasome enzyme system, Proteolea® assists in breaking down damaged or low-quality collagen fibers enabling the regeneration of fresh, healthy collagen.

3. Antioxidant and Blue Light Defence
Proteolea® offers antioxidant protection to help neutralise free radicals while assisting in defence against blue-light–induced oxidative stress

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